Principal Scientist
Company: Amazon Workforce Staffing
Location: Durham
Posted on: September 17, 2020
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Job Description:
Principal Scientist, Downstream Process Development Lead
Company: Sigma Xi, The Scientific Research Society Location: Cambridge Posted on: September 12, 2020 Job Description: Sigma Xi, The Scientific Research Society's Career
CenterPrincipal Scientist, Downstream Process Development Lead SB Principal Scientist, Downstream Process Development
LeadSolid’s Start : Solid is the English translation of Eytan,
theHebrew name of Solid’s co-founders Ilan and Annie Ganot’s
son,Eytani, who was diagnosed with Duchenne muscular
dystrophy(Duchenne) in 2012 at the age of 3. Unsatisfied with the
existingDuchenne treatment landscape, the Ganots built a
disease-focusedcompany with the people and potential to advance
innovative sciencequickly and responsibly. Solid’s Culture: Much of what you can learn about Solid and
ourculture can be found in our name. We come to work each day for
theDuchenne community, and that community is our family. We have
acollective strength and determination that propels us to
embraceinnovation and challenge the status quo because central to
all thatwe do is the unwavering commitment to advance meaningful
therapiesfor the Duchenne community. We are a fiercely passionate
andcommitted team, driven to collaborate with thoughtfulness
andrespect. We value exceptional skills, scientific
curiosity,entrepreneurial spirit, diversity and
adaptability.#TogetherWeAreSolid in our mission to find a cure for
Duchennemuscular dystrophy and we will not stop until we’ve done
it. Summary of role: Solid Biosciences is seeking an experienced Principal
Scientistto join our Process Development team and contribute to
thedevelopment of our downstream viral vector manufacturing
processes.This individual will join a dynamic and motivated team to
developand characterize unit operations in support of a mid to late
stageviral vector program, as well as tech transfer of the process
tothe clinical/commercial manufacturing team. Requirements The successful candidate will be responsible for leading a
teamof scientists and engineers on the design and execution
ofexperiments supporting troubleshooting,
development,characterization, scale-up, and transfer of the
downstreammanufacturing processes. They will also be responsible
forevaluation and implementation of new and existing
technology. What's in it for you? Opportunity to: Oversight, scheduling, planning and reviewing of viral
vectorprocess development and tech transfer experiments in the PD
labrelated to all downstream processes and in-process analytics,
toinclude process optimization and problem-solving processes
andequipment Lead a team of scientists and engineers focused on
developmentand optimization of viral vector purifications
processes Identify, evaluate, and implement new and existing
technologiesto improve process efficiency, control, and
understanding Coordinates with Upstream PD and analytical development
onmultiple projects simultaneously Apply DOE and other advanced statistical techniques to
designexperiments related to process development, characterization,
andscale-up Authoring of high-quality documents, including technicalreports,
presentations, SOPs, experimental protocols, andregulatory
filings Develops and mentor direct reports through
challengingassignments and providing constructive feedback, goal
setting andmonitoring performance on a routine and ensuring that
overallproject goals are on track Self-motivated, accountable, inquisitive, with
excellentorganizational and communication skills Flexibility to switch between projects Ability to lead/manage junior team members What we need from you: Ph.D. in Chemical Engineering or related field and 6+ years
ofexperience, Master’s or a Bachelor’s degree in the same field
with10+ years of experience in downstream process development Strong scientific skills and process development
experienceworking with gene therapy products Proven expertise in all downstream purification
conceptsincluding chromatographic separation, centrifugation,
filtration,and viral inactivation/removal Excellent technical, organizational,
interpersonal,collaborative, and verbal/written communication
skills - includingexcellent presentation skills and the ability to
communicate withemployees at all levels including senior
management Strong understanding of GxPs, process characterization,
andtechnology transfer Ability to manage, analyze, and interpret complex
experimentaldata Ability to apply engineering fundamentals to process design
andscale-up Ability to apply statistical tools for process
monitoring,experimental design, and data analysis Travel Commitment: Some travel may be required Job Information Job ID: 54026085 Location: Cambridge, Massachusetts, United States Position Title: Principal Scientist, Downstream
ProcessDevelopment Lead Company Name: Solid Bioscience Job Function: Scientist Job Type: Full-Time Job Duration: Indefinite Min Education: BA/BS/Undergraduate Min Experience: Over 10 Years Required Travel: 0-10% Jobs You May Like P Principal Scientist, Translational Modeling and... Cambridge, MA, United States AP Acceleron Pharma Cambridge, Massachusetts, United States P Scientist - High-throughput Protein Production Cambridge, MA, United States P Scientist - High-throughput Protein Production PO Box 13975 3200 Chapel Hill Nelson Blvd., Suite 300
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(919)549-4691 Keywords: Sigma Xi, The Scientific Research Society, Cambridge ,
Principal Scientist, Downstream Process Development Lead, Other ,
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Keywords: Amazon Workforce Staffing, Durham , Principal Scientist, Other , Durham, North Carolina
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