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POSTDOCTORAL ASSOCIATE

Company: Duke University
Location: Durham
Posted on: September 15, 2020

Job Description:

School of Medicine: Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked tenth among its peers, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where traditional barriers are low, interdisciplinary collaboration is embraced, and great ideas accelerate translation of fundamental scientific discoveries to improve humanhealth locally and around the globe. Comprised of 2,400 faculty physicians and researchers, the Duke University School of Medicine along with the Duke University School of Nursing and Duke University Health System create Duke Health. Duke Health is a world-class health care network. Founded in 1998 to provide efficient, responsive care, the health system offers a full network of health services and encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Private Diagnostic Clinic, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations. Job Description The National Institutes of Heal (NIH) has recently awarded Duke Anesthesiology and the Center forTranslational Pain Medicine (CTPM) a five-year, $8,566,593 million Center of Excellence award supported through the NIH's Program Project Grant (PPG) mechanism. This marks the founding of a new national center for pain research. The aims of the PPG are to identify novel complementary approaches to the treatment of pain conditions. The PPG will support the scientific development of the Center of Excellence and infrastructure for three scientific projects and three support cores. These units will further bring together Duke Anesthesiology's basic science and clinical groups to advance translational pain research. For this position, the candidate will work on one of the three center projects titled "Postoperative pain after bone fracture" that will be developed in close synergy with the three cores (Molecular, Behavioral and Administrative). This projectis co-led by Dr. Terrando and Dr. Jordt and seeks to: 1) Analyze the effects of stress and sex on surgery-induced neuroinflammation and pain behavior2) Determine the effects of natural compounds including docosahexaenoic acids and natural cooling agents on neuro inflammation and pain behavior after orthopedic surgery3) Characterize the effects of bioelectronic approaches (electro acupuncture and vagus nerve stimulation) to reduce pain and immune cell activation after orthopedic surgery, and use fluorescent viral tracing approaches to mapanalgesic circuits. Preferrred Requirements:A Ph.D. degree in Neuroscience, Immunology or related fields. Experience with mouse models, biochemistry/molecular biology, and immune-histology is required. The candidate will work in a strong interdisciplinary and collaborative environment at Duke University and Duke Medical Center. Key guiding questions include:(i) what are the factors that contribute to postoperative pain chronicity?(ii) how inflammation affects glial function and activity? (iii) how complementary approaches, including natural supplements and vagus nerve stimulation, modulate pain behavior and cognition?(iii) map the neuronal circuitry activated by analgesic interventions. Min Education and Degree Requirements: Ph.D. or equivalent doctorate (e.g. Sc.D., M.D., D.V.M.). Other Credential/Experiential Requirements: The incumbent must be a true post-doctoral fellow registered with the Post Doc Office Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status. Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values. Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

Keywords: Duke University, Durham , POSTDOCTORAL ASSOCIATE, Other , Durham, North Carolina

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