SCIENTIFIC/RESEARCH LABORATORY MANAGER
Company: Duke University
Posted on: November 18, 2023
School of Medicine Established in 1930, Duke University School
of Medicine is the youngest of the nation's top medical schools.
Ranked sixth among medical schools in the nation, the School takes
pride in being an inclusive community of outstanding learners,
investigators, clinicians, and staff where interdisciplinary
collaboration is embraced and great ideas accelerate translation of
fundamental scientific discoveries to improve human health locally
and around the globe. Composed of more than 2,500 faculty
physicians and researchers, more than 1,300 students, and more than
6,000 staff, the Duke University School of Medicine along with the
Duke University School of Nursing, Duke University Health System
and the Private Diagnostic Clinic (PDC) comprise Duke Health. a
world-class academic medical center. The Health System encompasses
Duke University Hospital, Duke Regional Hospital, Duke Raleigh
Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and
Wellness, and multiple affiliations.
Scientific Research Laboratory Manager
Flow Cytometry Facility - Duke Human Vaccine Institute
The DHVI Flow Cytometry Facility has been providing
state-of-the-art flow-based analysis and cell sorting for over 25
years. The Facility currently has two BD Symphony S6 sorters, one
BD FACSAriaIII sorter, one BD Symphony A5 analyzer, one BD
LSRFortessa analyzer, one BD LSRII analyzer, and one Sartorius
iQue3 Screener. The facility has three full-time staff members,
supports 120+ principal investigators, provides comprehensive
training for 24/7 independent use of analytical instruments, and
sorts samples at Biosafety levels 1, 2 and 3, including CDC Select
The DHVI Flow Cytometry Facility has laboratories on Duke's main
campus and on Duke's Research and Discovery@RTP campus. The
Research Laboratory Manager position will be responsible for
running the day-to-day operations of the facility, supervising
facility personnel, operating cytometers as needed, and
implementing innovative cytometry-based approaches in support of
the scientific research activities of the Duke Human Vaccine
Institute and collaborating entities.
- Collaborate with the DHVI Flow Cytometry Facility Director and
the DHVI Administrative Manager for Finance to formulate short- and
long-range goals for the scientific and financial operation of the
Facility. Set priorities, assign responsibilities, and develop
annual business plans and rates/fees for revenue neutrality.
Prepare technical reports as needed reflecting volume of work,
procedures utilized and study results. Coordinate the preparation
of reports and analyses setting forth progress, adverse trends, and
appropriate recommendations or conclusions. Work with the DHVI Flow
Cytometry Facility Director on the preparation of equipment
- Manage the Flow Facility technical staff including recruitment
and selection, performance management, and professional/skill
development. Train, teach, and mentor staff as required.
- Collaborate with DHVI leadership and Principal Investigators to
bring new innovative flow-based applications and approaches to the
Flow Facility. Collaborate on preparing and completing research
grants, contracts, scientific projects, and manuscripts. It is
hoped that the Flow Facility Manager will become a full
collaborative partner in all flow-based DHVI research.
- Perform other duties as requested by the DHVI Flow Cytometry
Facility Director, Shared Resources Scientific Director, COO, and
Director. Instrument Operation (40%)
- Run Cell Sorters/Analyzers to meet the needs of facility end
users, as directed by the Facility Director, Manager and DHVI
- Ensure that all Flow Facility work is performed under
DHVI-approved Standard Operating Procedures (SOPs) and provide
day-to-day monitoring of safe work practices in the Facility to
ensure full compliance with all safety regulations/SOPs.
- Ensure all Flow Facility instruments are properly maintained
and functioning at optimal performance levels. Develop and
implement a real-time reporting system for instrument QA and
service logs. Ensure all data generated in the facility
appropriately archived in a timely manner to ensure data integrity,
provenance and long-term retrieval
- Coordinate resource and staff scheduling to meet the needs of
all facility users. Provide back-up operator coverage on all
facility instruments as needed. User Training (20%)
- Provide training to new facility users for independent
operation of an analysis flow cytometer, including instrument QC,
experimental controls, sample acquisition, instrument shutdown, and
- Expand the existing Flow Facility training program (instrument
operation) to include introductory and advanced flow techniques
(e.g. sample preparation, panel development, and data
The successful candidate will be willing and able to:
- Work with hazardous biological agents handled at BSL2 and
- Comply with vaccination requirements when necessary
- Complete US Department of Justice screening for Select Agent
- Complete Select Agent registration at Tier 1
- Achieve external certification for independent work at BSL3
REQUIRED QUALIFICATIONS AT THIS LEVEL:
- Education/Training: Bachelor's degree in a scientific
discipline or in the health or physical sciences. Master's degree
preferred. Ph.D. highly preferred.
- Experience: Minimum of seven years of experience. Must have
previous experience managing projects. Experience must include a
minimum of three years in a supervisory/managerial role.
- Experience operating BD FACS Aria and/or Symphony
- Experience with complex polychromatic panel development and
data analysis for surface and intracellular phenotyping for basic
(mouse, non-human primate) and clinical studies (human).
- Experience in Biosafety Level 3 containment.
Duke is an Affirmative Action/Equal Opportunity Employer committed
to providing employment opportunity without regard to an
individual's age, color, disability, gender, gender expression,
gender identity, genetic information, national origin, race,
religion, sex, sexual orientation, or veteran status.
Duke aspires to create a community built on collaboration,
innovation, creativity, and belonging. Our collective success
depends on the robust exchange of ideas-an exchange that is best
when the rich diversity of our perspectives, backgrounds, and
experiences flourishes. To achieve this exchange, it is essential
that all members of the community feel secure and welcome, that the
contributions of all individuals are respected, and that all voices
are heard. All members of our community have a responsibility to
uphold these values.
Essential Physical Job Functions: Certain jobs at Duke University
and Duke University Health System may include essentialjob
functions that require specific physical and/or mental abilities.
Additional information and provision for requests for reasonable
accommodation will be provided by each hiring department.
Keywords: Duke University, Durham , SCIENTIFIC/RESEARCH LABORATORY MANAGER, Healthcare , Durham, North Carolina
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