Director/Senior Director of Statistical Science - Statistical Innovation
Company: AstraZeneca
Location: Timberlake
Posted on: August 6, 2022
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Job Description:
Director/Senior Director of Statistical Science - Statistical
Innovation Location: Cambridge or Macclesfield (UK) Gaithersburg,
Durham, Waltham, Wilmington (US) Gothenburg (Sweden) DescriptionDo
you have a passion for developing and aiding implementation of
innovative statistical approaches and methods in clinical studies?
Are you up for the challenge to impact a company that follows the
science and turns ideas into life changing medicines? If yes, we
welcome you to join AstraZeneca! At AstraZeneca, we put patients
first and strive to meet their unmet needs worldwide, while
applying leading edge approaches to science across many business
areas. Working here means being entrepreneurial, thinking big and
working together to make the impossible a reality. If you are swift
to act, confident to lead, willing to collaborate, and curious
about what science can do, then you''re our kind of person.We are
recruiting a Statistical Science Director to join our growing
Statistical Innovation group. Our main focus is providing
statistical methodology support for all phases of clinical
development for AZ''s Cardiovascular, Renal & Metabolism and
Respiratory & Immunology divisions together with specific targeted
support for the Oncology division and the newly acquired Alexion
division of AZ which specializes in medicines to treat rare
diseases. In this role, you will belong to the Early Biometrics &
Statistical Innovation (EB&SI) department, where our
data-centric focus helps us work efficiently and creatively to
bring the right medicines to the right patients. Our teams use
their expertise in statistics and programming to address drug
development objectives and reduce uncertainty in product
development, driving better business decisions with quantitative
reasoning. As part of the Data Science & AI team, you''ll use
technology at the forefront of science in a creative environment,
with the scope to develop new statistical ideas and apply them in
your work. Main duties and responsibilitiesJoining a team of
statistical methodology experts, you will provide key input as you
work to find solutions to problems at critical stages in the drug
development cycle. This is exciting and technically challenging
work in a dynamic and constantly changing landscape. Your key focus
will be on producing pragmatic solutions, often within a tight time
scale where the emphasis will be to deliver first, then refine and
develop your solutions thereafter.You will contribute to, or lead
capability build in more than one of the following statistical
areas: Design of early and late phase clinical studies: including
group sequential and adaptive designs using both frequentist and
Bayesian approaches.Methods to analyse data collected in real-time,
Estimands, Missing Data, Subgroup and Biomarkers.You will also
provide expert consultancy on key issues for fellow statisticians
working in our therapeutically aligned statistics groups, as well
as medical scientists and other key roles across the business. This
will involve leading and participating in strategic activities such
as capability build projects, which can directly impact
improvements to the way clinical trials are designed and analysed
in AstraZeneca. As well as developing and implementing new
methodology, interacting with external scientists and regulators,
through publications, presentations and cross-industry
collaborations. There will also be a focus to proactively identify
new areas where Statistical Innovation can add value, developing
collaborative relationships with the external scientific/academic
community.RequirementsEssential PhD in Statistics or a related
discipline, followed by extensive experience of independent
academic research and/or clinical drug developmentDocumented
ability of delivering innovative statistical solutions in an
applied environment (related to at least two of the following areas
or being externally recognized as an expert in at least one of
these areas): Design of early and late phase clinical studies:
including group sequential and adaptive designs. Analysis of data
collected in real-time (e.g. sensor data), Missing data and
Estimands, Subgroups and Biomarkers)Strong knowledge of programming
in R and/or SASHigh level of competence in global and cross-skilled
collaborative workingExtensive track record of research and
methodological development in Statistics, supported by scientific
publications in first class statistical journalsDesire to apply
your scientific competence on practical problems, for the benefit
of patientsDesirable Knowledge / research experience in the other
areas such as development of statistical methodology related to the
analysis and interpretation of safety data, observational studies,
meta-analysis, non-linear and mixed effect models.Broad awareness
of statistical issues against the evolving scientific and
regulatory landscapeTo be considered for the Senior Director of
Statistical Science role, candidates should be externally
recognized as an expert in multiple of the areas listed above, have
a proven track record of collaborations with external groups to
produce high quality research.Why AstraZeneca?It''s a place to
think differently - to find new ways of handling and treating
diseases. We are trusted and empowered to explore. Ultimately,
it''s more than a job. We know that our work impacts people with
serious conditions, many of whom have no other alternatives.
That''s what drives us - the potential to impact over one billion
patients worldwide.So, what''s next! If this sounds like your next
challenge - apply today! We look forward to get to know you better.
Welcome to send us your application through our website at your
earliest convenience, but no later thanWhere can I find out
more?Follow AstraZeneca on LinkedIn: AstraZeneca on Instagram: more
about BioPharmaceuticals R&D: dedicated Biometrics landing page
is: advert started: 1st July 2022Date advert ends: 1st August
2022AstraZeneca embraces diversity and equality of opportunity. We
are committed to building an inclusive and diverse team
representing all backgrounds, with as wide a range of perspectives
as possible, and harnessing industry-leading skills. We believe
that the more inclusive we are, the better our work will be. We
welcome and consider applications to join our team from all
qualified candidates, regardless of their characteristics. We
comply with all applicable laws and regulations on
non-discrimination in employment (and recruitment), as well as work
authorization and employment eligibility verification
requirements.AstraZeneca requires all US employees to be fully
vaccinated for COVID-19 but will consider requests for reasonable
accommodations as required by applicable law. - provided by
Dice
Keywords: AstraZeneca, Durham , Director/Senior Director of Statistical Science - Statistical Innovation, Executive , Timberlake, North Carolina
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